Multi-trait genome-wide association study identifies a novel endometrial cancer risk locus that associates with testosterone levels
- Creator: Wang, Xuemin , Kho, Pik Fang , Dörk, Thilo , Spurdle, Amanda B. , Glubb, Dylan M. , O'Mara, Tracy A. , Ramachandran, Dhanya , Bafligil, Cemsel , Amant, Frederic , Goode, Ellen L. , Scott, Rodney J. , Tomlinson, Ian , Evans, D. Gareth , Crosbie, Emma J.
- Resource Type: journal article
- Date: 2023
Multi-tissue transcriptome-wide association study identifies eight candidate genes and tissue-specific gene expression underlying endometrial cancer susceptibility
- Creator: Kho, Pik Fang , Wang, Xuemin , Cuellar-Partida, Gabriel , Dork, Thilo , Goode, Ellen L. , Lambrechts, Diether , Scott, Rodney J. , Spurdle, Amanda B. , O'Mara, Tracy A. , Glubb, Dylan M.
- Resource Type: journal article
- Date: 2021
Genetic overlap between endometriosis and endometrial cancer: Evidence from cross-disease genetic correlation and GWAS meta-analyses
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Henders, Anjali K. , Attia, John , McEvoy, Mark , Holliday, Elizabeth G. , Scott, Rodney J. , Webb, Penelope M. , Fasching, Peter A. , Beckmann, Matthias W. , Ekici, Arif B. , Hein, Alexander , Morris, Andrew P. , Rübner, Matthias , Hall, P , Czene, K , Dörk, T , Dürst, M , Hillemanns, P , Runnebaum, I , Lambrechts, D , Amant, F , Annibali, D , Cheng, Timothy H. T. , Depreeuw, J , Vanderstichele, A , Goode, EL , Cunningham, JM , Dowdy, SC , Winham, SJ , Trovik, J , Hoivik, E , Werner, HMJ , Krakstad, C , Gorman, Maggie , Ashton, Katie , Otton, Geoffrey , Proietto, Tony , Tham, E , Mints, M , Ahmed, S , Healey, CS , Shah, M , Pharoah, PDP , Dunning, AM , Martin, Lynn , Dennis, J , Bolla, MK , Michailidou, K , Wang, Q , Tyrer, JP , Hopper, JL , Peto, J , Swerdlow, AJ , Burwinkel, B , Brenner, H , Hodson, Shirley , Meindl, A , Brauch, H , Lindblom, A , Chang-Claude, J , Couch, FJ , Giles, GG , Kristensen, VN , Cox, A , Zondervan, KT , Nyholt, DR , Jones, Angela , Macgregor, S , Montgomery, GW , Martin, Nnicholas G. , Gordon, Scott
- Resource Type: journal article
- Date: 2018
Identification of nine new susceptibility loci for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Amant, Frederic , Annibali, Daniela , Ashton, Katie , Attia, John , Auer, Paul L. , Beckmann, Matthias W. , Black, Amanda , Bolla, Manjeet K. , Brauch, Hiltrud , Brenner, Hermann , Brinton, Louise , Buchanan, Daniel D. , Burwinkel, Barbara , Chang-Claude, Jenny , Chanock, Stephen J. , Chen, Chu , Chen, Maxine M. , Cheng, Timothy H. T. , Clarke, Christine L. , Holliday, Elizabeth G. , McEvoy, Mark , Otton, Geoffrey , Proietto, Tony , Scott, Rodney J.
- Resource Type: journal article
- Date: 2018
A common variant at the 14q32 endometrial cancer risk locus activates AKT1 through YY1 binding
- Creator: Painter, Jodie N. , Kaufmann, Susanne , Hoivik, Erling A. , Goode, Ellen L. , Scott, Rodney J. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , French, Juliet D. , Salvesen, Helga B. , Pollock, Pamela M. , Thompson, Deborah J. , O'Mara, Tracy A. , Spurdle, Amanda B. , Edwards, Stacey L. , Hillman, Kristine M. , Sivakumaran, Haran , Darabi, Hatef , Cheng, Timothy H.T. , Pearson, John , Kazakoff, Stephen , Waddell, Nicola
- Resource Type: journal article
- Date: 2016
CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer
- Creator: Thompson, Deborah J. , O'Mara, Tracy A. , Martin, Lynn , Hodgson, Shirley , Michailidou, Kyriaki , Tyrer, Jonathan P. , Maranian, Mel J. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Fasching, Peter A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Scott, Rodney J , McEvoy, Mark , Attia, John , Holliday, Elizabeth G. , Painter, Jodie N. , Cheng, Timothy , Folkerd, Elizabeth , Doody, Deborah , Dennis, Joe , Webb, Penelope M. , Gorman, Maggie
- Resource Type: journal article
- Date: 2016
Five endometrial cancer risk loci identified through genome-wide association analysis
- Creator: Cheng, Timothy H. T. , Thompson, Deborah J. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Webb, Penelope M. , Australian National Endometrial Cancer Study Group (ANECS), , Attia, John , Holliday, Elizabeth G. , McEvoy, Mark , Scott, Rodney J. , O'Mara, Tracy A. , Dowdy, Sean C. , Ashton, Katie , Otton, Geoffrey , Proietto, Tony , Painter, Jodie N. , Glubb, Dylan M. , Flach, Susanne , Lewis, Annabelle , French, Juliet D. , Freeman-Mills, Luke , Church, David
- Resource Type: journal article
- Date: 2016
Genetic risk score mendelian randomization shows that obesity measured as body mass index, but not waist:hip ratio, is causal for endometrial cancer
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Scott, Rodney J. , Ahmed, Shahana , Healey, Catherine S. , Shah, Mitul , Gorman, Maggie , Martin, Lynn , Hodgson, Shirley V. , Beckmann, Matthias W. , Ekici, Arif B. , Fasching, Peter A. , Marquart, Louise , Hein, Alexander , Rübner, Matthias , Czene, Kamilla , Darabi, Hatef , Hall, Per , Li, Jingmei , Dörk, Thilo , Dürst, Matthias , Hillemanns, Peter , Runnebaum, Ingo B. , Webb, Penelope M. , Amant, Frederic , Annibali, Daniela , Depreeuw, Jeroen , Lambrechts, Diether , Neven, Patrick , Cunningham, Julie M. , Dowdy, Sean C. , Goode, Ellen L. , Fridley, Brooke L. , Winham, Stacey J. , Attia, John , Njølstad, Tormund S. , Salvesen, Helga B. , Trovik, Jone , Werner, Henrica M. J. , Ashton, Katie A. , Otton, Geoffrey , Proietto, Anthony , Mints, Miriam , Tham, Emma , Bolla, Manjeet K. , Medland, Sarah E. , Michailidou, Kyriaki , Wang, Qin , Tyrer, Jonathan P. , Hopper, John L. , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Brauch, Hiltrud , Cheng, Timothy , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Tomlinson, Ian , Dunning, Alison M. , Easton, Douglas F. , Dennis, Joe , Thompson, Deborah J. , Spurdle, Amanda B. , Holliday, Elizabeth G. , McEvoy, Mark
- Resource Type: journal article
- Date: 2016
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer
- Creator: Chen, Maxine M. , O'Mara, Tracy A. , Cheng, Timothy H. T. , Cook, Linda S. , Crous-Bou, Marta , Doherty, Jennifer , Friedenreich, Christine M. , Garcia-Closas, Montserrat , Gaudet, Mia M. , Gorman, Maggie , Haiman, Christopher , Hankinson, Susan E. , Thompson, Deborah J. , Holliday, Elizabeth G. , Painter, Jodie N. , Australian National Endometrial Cancer Study Group (ANECS), , Attia, John , Black, Amanda , Brinton, Louise , Chanock, Stephen , Chen, Chu
- Resource Type: journal article
- Date: 2016
Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer
- Creator: O'Mara, Tracy A. , Glubb, Dylan M. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Shah, Mitul , Ahmed, Shahana , Healey, Catherine S. , Gorman, Maggie , Martin, Lynn , National Study of Endometrial Cancer Genetics Group (NSECG), , Hodgson, Shirley , Painter, Jodie N. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Ekici, Arif B. , Hall, Per , Czene, Kamila , Darabi, Hatef , Li, Jingmei , Dürst, Matthias , Runnebaum, Ingo , Cheng, Timothy , Hillemanns, Peter , Dörk, Thilo , Lambrechts, Diether , Depreeuw, Jeroen , Annibali, Daniela , Amant, Frederic , Zhao, Hui , Goode, Ellen L. , Dowdy, Sean C. , Fridley, Brooke L. , Dennis, Joe , Winham, Stacey J. , Salvesen, Helga B. , Njølstad, Tormund S. , Trovik, Jone , Werner, Henrica M. J. , Tham, Emma , Liu, Tao , Mints, Miriam , RENDOCAS, , Bolla, Manjeet K. , Australian National Endometrial Cancer Study Group (ANECS), , Michailidou, Kyriaki , Tyrer, Jonathan P. , Wang, Qin , Hopper, John L. , AOCS Group, , Peto, Julian , Swerdlow, Anthony J. , Burwinkel, Barbara , Brenner, Hermann , Meindl, Alfons , Attia, John , Brauch, Hiltrud , Lindblom, Annika , Chang-Claude, Jenny , Couch, Fergus J. , Giles, Graham G. , Kristensen, Vessela N. , Cox, Angela , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Holliday, Elizabeth G. , Easton, Douglas F. , Thompson, Deborah J. , Spurdle, Amanda B. , McEvoy, Mark , Scott, Rodney J.
- Resource Type: journal article
- Date: 2015
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Healey, Catherine S. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Kaufmann, Susanne , Shah, Mitul , French, Juliet D. , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Easton, Douglas F. , Edwards, Stacey L. , Thompson, Deborah J. , Spurdle, Amanda B. , Hillman, Kristine M. , Walpole, Carina , Moya, Leire , Pollock, Pamela , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Batra, Jyotsna , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , CHIBCHA Consortium , De Polanco, Ma. Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Santos, Erika , Teixeira, Manuel R. , Cheng, Timothy , Carvajal-Carmona, Luis , Shu, Xiao-Ou , Long, Jirong , Zheng, Wei , Xiang, Yong-Bing , The Australian National Endometrial Cancer Study Group (ANECS) , Montgomery, Grant W. , Webb, Penelope M. , Scott, Rodney J. , McEvoy, Mark , Lose, Felicity A. , Attia, John , Holliday, Elizabeth , Martin, Nicholas G. , Nyholt, Dale R. , Henders, Anjali K. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Dennis, Joe , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Michailidou, Kyriaki , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Werner, Henrica M. J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Tzortzatos, Gerasimos , Mints, Miriam , Tyrer, Jonathan P. , Tham, Emma , RENDOCAS , Hall, Per , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS) , Ekici, Arif B. , Ahmed, Shahana , Ruebner, Matthias , Johnson, Nicola , Peto, Julian , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Miendl, Alfons , Brauch, Hiltrud , The GENICA Network, , Ferguson, Kaltin , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olsen, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunnigham, Julie M.
- Resource Type: journal article
- Date: 2015
Genome-wide association study of endometrial cancer in E2C2
- Creator: De Vivo, Immaculata , Prescott, Jennifer , Cook, Linda S. , Crous-Bou, Marta , Doherty, Jennifer , Dunning, Alison M. , Easton, Douglas F. , Friedenreich, Christine M. , Garcia-Closas, Montserrat , Gaudet, Mia M. , Haiman, Christopher , Hankinson, Susan E. , Setiawan, Veronica Wendy , Hartge, Patricia , Henderson, Brian E. , Holliday, Elizabeth , Horn-Ross, Pamela L. , Hunter, David J. , Le Marchand, Loic , Liang, Xiaolin , Lissowska, Jolanta , Long, Jirong , Lu, Lingeng , Olson, Sara H. , Magliocco, Anthony M. , McEvoy, Mark , O'Mara, Tracy A. , Orlow, Irene , Painter, Jodie N. , Pooler, Loreall , Rastogi, Radhai , Rebbeck, Timothy R. , Risch, Harvey , Sacerdote, Carlotta , Wentzensen, Nicolas , Schumacher, Frederick , Scott, Rodney J. , Sheng, Xin , Shu, Xiao-ou , Spurdle, Amanda B. , Thompson, Deborah , VanDen Berg, David , Weiss, Noel S. , Xia, Lucy , Xiang, Yong-Bing , Attia, John , Yang, Hannah P. , Yu, Herbert , Zheng, Wei , Chanock, Stephen , Kraft, Peter , Black, Amanda , Brinton, Louise , Chen, Chu , Chen, Constance
- Resource Type: journal article
- Date: 2014